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Tchesnokov EP

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Publications:

Title Authors Year Journal
Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. Tchesnokov EP 2011 The Journal of biological chemistry
Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase. Tchesnokov EP 2009 The Journal of biological chemistry
Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme. Tchesnokov EP 2009 The Journal of biological chemistry
Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase. Tchesnokov EP 2008 The Journal of biological chemistry
Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Tchesnokov EP 2008 Cell Host Microbe
Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors". Tchesnokov EP 2008 The Journal of biological chemistry
Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms. Tchesnokov EP 2008 The Journal of biological chemistry
The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. Tchesnokov EP 2007 The Journal of biological chemistry
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet. Tchesnokov EP 2006 J Virol
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