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Herdewijn P

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Publications:

Title Authors Year Journal
A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates. Herdewijn P 2013 Chemistry & biology
Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Herdewijn P 2012 Chemistry (Weinheim an der Bergstrasse, Germany)
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. Herdewijn P 2005 Journal of the American Chemical Society
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. Herdewijn P 2003 Journal of medicinal chemistry
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Herdewijn P 1991 Proceedings of the National Academy of Sciences of the United States of America
Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound. Herdewijn P 1991 Proceedings of the National Academy of Sciences of the United States of America
Differential inhibitory effects of several pyrimidine 2',3'-dideoxynucleoside 5'-triphosphates on the activities of reverse transcriptase and various cellular DNA polymerases. Herdewijn P 1989 Molecular pharmacology
Alpha, beta- and beta, gamma-methylene 5'-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine-5'-triphosphate. Correlation between affinity for reverse transcriptase, susceptibility to hydrolysis by phosphodiesterases and anti-retrovirus activity. Herdewijn P 1988 Biochemical pharmacology
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