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Zhang H

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Publications:

Title Authors Year Journal
Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. Zhang H 2010 The Journal of biological chemistry
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W. Zhang H 2010 Journal of molecular biology
RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity. Zhang H 2009 Biochemistry
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. Zhang H 2009 The Journal of biological chemistry
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. Zhang H 2009 The Journal of biological chemistry
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. Zhang H 2009 The Journal of biological chemistry
Domain architecture and biochemical characterization of vertebrate Mcm10. Zhang H 2008 The Journal of biological chemistry
Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphates. Zhang H 2007 Nucleic acids research
The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Zhang H 2006 Biochemistry
Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Zhang H 2002 Eur J Biochem
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. Zhang H 1999 J Med Chem
Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate synthase-inhibited cells using a modified DNA polymerase assay. Zhang H 1997 Biochem Pharmacol
Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127. Zhang H 1995 Antiviral research
Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. Zhang H 1993 Proceedings of the National Academy of Sciences of the United States of America
HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase. Zhang H 1993 Virology

Version:20241007

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