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Furman PA

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Publications:

Title Authors Year Journal
Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Furman PA 2004 Antimicrobial agents and chemotherapy
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine. Furman PA 2001 Antimicrobial agents and chemotherapy
Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate. Furman PA 1996 The Journal of biological chemistry
Mechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosine. Furman PA 1993 Proceedings of the National Academy of Sciences of the United States of America
Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding. Furman PA 1993 Proceedings of the National Academy of Sciences of the United States of America
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection. Furman PA 1985 Proceedings of the National Academy of Sciences of the United States of America
Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase. Furman PA 1984 The Journal of biological chemistry
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U. Furman PA 1984 Antimicrob Agents Chemother
Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin. Furman PA 1983 Nucleic acids research
Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine. Furman PA 1982 Journal of virology
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities. Furman PA 1981 J Virol
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. Furman PA 1979 J Virol

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