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Randell JC

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Publications:

Title Authors Year Journal
Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication. Randell JC 2007 J Virol
Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. Randell JC 2007 Journal of virology
Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis. Randell JC 2005 Journal of virology
The herpes simplex virus processivity factor, UL42, binds DNA as a monomer. Randell JC 2004 Journal of molecular biology
Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor. Randell JC 2001 Molecular cell
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