Sharkey DJ
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Publications:
Title | Authors | Year | Journal |
---|---|---|---|
Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. | Sharkey DJ | 1998 | Proceedings of the National Academy of Sciences of the United States of America |
Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. | Sharkey DJ | 1998 | Protein Eng |
Topographical characterization of the DNA polymerase from Thermus aquaticus. Defining groups of inhibitor mAbs by epitope mapping and functional analysis using surface plasmon resonance. | Sharkey DJ | 1995 | J Immunol Methods |
Characterization of crystals of the thermostable DNA polymerase I from Thermus aquaticus. | Sharkey DJ | 1995 | Proteins |
Monoclonal antibodies prepared against the DNA polymerase from Thermus aquaticus are potent inhibitors of enzyme activity. | Sharkey DJ | 1994 | J Immunol Methods |