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Sharkey DJ

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Publications:

Title Authors Year Journal
Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. Sharkey DJ 1998 Proceedings of the National Academy of Sciences of the United States of America
Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Sharkey DJ 1998 Protein Eng
Characterization of crystals of the thermostable DNA polymerase I from Thermus aquaticus. Sharkey DJ 1995 Proteins
Topographical characterization of the DNA polymerase from Thermus aquaticus. Defining groups of inhibitor mAbs by epitope mapping and functional analysis using surface plasmon resonance. Sharkey DJ 1995 J Immunol Methods
Monoclonal antibodies prepared against the DNA polymerase from Thermus aquaticus are potent inhibitors of enzyme activity. Sharkey DJ 1994 J Immunol Methods

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