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Locatelli GA

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Publications:

Title Authors Year Journal
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen. Locatelli GA 2010 Biochem J
DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A. Locatelli GA 2005 The Journal of biological chemistry
Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhibition by efavirenz. Locatelli GA 2005 Antimicrobial agents and chemotherapy
HIV-1 reverse transcriptase inhibitors: current issues and future perspectives. Locatelli GA 2004 Current drug metabolism
Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. Locatelli GA 2001 Proceedings of the National Academy of Sciences of the United States of America
The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors. Locatelli GA 2001 The Journal of biological chemistry

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