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Canard B

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Publications:

Title Authors Year Journal
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations. Canard B 2004 The Journal of biological chemistry
A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions. Canard B 2004 The Journal of biological chemistry
The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer. Canard B 2003 The Journal of biological chemistry
The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity. Canard B 1999 The Journal of biological chemistry
Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer. Canard B 1998 The Journal of biological chemistry
Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/template. Canard B 1997 Proceedings of the National Academy of Sciences of the United States of America
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