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Rösner M

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Publications:

Title Authors Year Journal
The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance. Rösner M 2001 Journal of molecular biology
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance. Rösner M 1998 Journal of molecular biology
In vitro selection for different mutational patterns in the HIV-1 reverse transcriptase using high and low selective pressure of the nonnucleoside reverse transcriptase inhibitor HBY 097. Rösner M 1997 Virology
Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants. Rösner M 1996 Proceedings of the National Academy of Sciences of the United States of America
Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication. Rösner M 1995 Antimicrobial agents and chemotherapy
Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Rösner M 1993 Antimicrobial agents and chemotherapy

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