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Florián J

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Publications:

Title Authors Year Journal
DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Florián J 2008 Biochemistry
Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Florián J 2007 Biochemistry
DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. Florián J 2007 FEBS letters
Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol beta. Florián J 2006 Biochemistry
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. Florián J 2005 Proceedings of the National Academy of Sciences of the United States of America
Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase. Florián J 2003 Journal of the American Chemical Society
Computer simulation studies of the fidelity of DNA polymerases. Florián J 2003 Biopolymers
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