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Tanaka H

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Publications:

Title Authors Year Journal
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile. Tanaka H 2009 Antimicrobial agents and chemotherapy
Ctf4 coordinates the progression of helicase and DNA polymerase alpha. Tanaka H 2009 Genes Cells
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate. Tanaka H 2008 Antimicrobial agents and chemotherapy
Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT. Tanaka H 2007 Antiviral Res
4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants. Tanaka H 2005 Antivir Chem Chemother
Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma. Tanaka H 2004 Journal of gastroenterology and hepatology
Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. Tanaka H 1999 J Med Chem
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. Tanaka H 1996 J Med Chem
Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro. Tanaka H 1994 Antimicrobial agents and chemotherapy
Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives. Tanaka H 1991 Molecular pharmacology
Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase. Tanaka H 1991 Proceedings of the National Academy of Sciences of the United States of America
Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative. Tanaka H 1989 Biochemical and biophysical research communications

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