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Chu CK

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Publications:

Title Authors Year Journal
Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma. Chu CK 2007 Antivir Chem Chemother
D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance. Chu CK 2007 Journal of medicinal chemistry
Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis. Chu CK 2003 Biochemistry
Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase. Chu CK 2003 Antivir Chem Chemother
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine. Chu CK 2001 Antimicrobial agents and chemotherapy
In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine. Chu CK 2000 Antimicrobial agents and chemotherapy
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. Chu CK 1993 Antimicrob Agents Chemother
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