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Summerer D

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Publications:

Title Authors Year Journal
Application of the C4'-alkylated deoxyribose primer system (CAPS) in allele-specific real-time PCR for increased selectivity in discrimination of single nucleotide sequence variants. Summerer D Biological chemistry
Chemical biology of DNA polymerases: from selectivity to new functions. Summerer D 2007 Nucleic acids symposium series (2004)
Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design. Summerer D 2005 Angewandte Chemie (International ed. in English)
4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase. Summerer D 2005 Bioorganic & medicinal chemistry letters
Increased single-nucleotide discrimination of PCR by primer probes bearing hydrophobic 4'C modifications. Summerer D 2004 Chembiochem : a European journal of chemical biology
Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands. Summerer D 2002 Journal of the American Chemical Society
Varied DNA polymerase-substrate interactions in the nucleotide binding pocket. Summerer D 2002 Chembiochem
A molecular beacon for quantitative monitoring of the DNA polymerase reaction in real-time. Summerer D 2002 Angewandte Chemie (International ed. in English)
DNA Polymerase Selectivity: Sugar Interactions Monitored with High-Fidelity Nucleotides This work was supported by a grant from the Deutsche Forschungsgemeinschaft. We thank Professor Dr. Michael Famulok for his continuing support. Summerer D 2001 Angewandte Chemie (International ed. in English)
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