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Cushman M

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Publications:

Title Authors Year Journal
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. Cushman M 2009 J Med Chem
Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Cushman M 2009 European journal of medicinal chemistry
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors. Cushman M 2008 Bioorganic & medicinal chemistry letters
Inhibition of tubulin polymerization by select alkenyldiarylmethanes. Cushman M 2008 Bioorganic & medicinal chemistry letters
Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems. Cushman M 2007 Journal of medicinal chemistry
Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability. Cushman M 2007 Journal of medicinal chemistry
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. Cushman M 2006 Bioorganic & medicinal chemistry
Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents. Cushman M 2006 Journal of medicinal chemistry
Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors. Cushman M 2005 Journal of medicinal chemistry
Design, synthesis, anti-HIV activities, and metabolic stabilities of alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors. Cushman M 2004 Journal of medicinal chemistry
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain. Cushman M 2000 Bioorganic & medicinal chemistry
New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors. Cushman M 1998 Journal of medicinal chemistry
Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight. Cushman M 1991 Journal of medicinal chemistry
Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds. Cushman M 1991 Journal of medicinal chemistry
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