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Paessens A

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Publications:

Title Authors Year Journal
Resistance mutations selected in vivo under therapy with anti-HIV drug HBY 097 differ from resistance pattern selected in vitro. Paessens A 1999 Antiviral research
In vitro selection for different mutational patterns in the HIV-1 reverse transcriptase using high and low selective pressure of the nonnucleoside reverse transcriptase inhibitor HBY 097. Paessens A 1997 Virology
Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants. Paessens A 1996 Proceedings of the National Academy of Sciences of the United States of America
Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication. Paessens A 1995 Antimicrobial agents and chemotherapy
Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720. Paessens A 1994 Journal of virology
Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Paessens A 1993 Antimicrobial agents and chemotherapy
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