
Brindisi M
Publications:
Title | Authors | Year | Journal |
---|---|---|---|
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. | Brindisi M | 2011 | Bioorganic & medicinal chemistry letters |
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. | Brindisi M | 2009 | Journal of medicinal chemistry |
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. | Brindisi M | 2008 | Biochemical pharmacology |
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