
Giorgi G
Publications:
Title | Authors | Year | Journal |
---|---|---|---|
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. | Giorgi G | 2009 | Journal of medicinal chemistry |
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. | Giorgi G | 2009 | Journal of medicinal chemistry |
The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors. | Giorgi G | 2001 | The Journal of biological chemistry |
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