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Kirby KA

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Publications:

Title Authors Year Journal
Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients. Kirby KA 2013 Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Effects of 4' - and 2-Substitutions on the Bioactivity of 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine. Kirby KA 2013 Antimicrobial agents and chemotherapy
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA. Kirby KA 2013 Retrovirology
HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors. Kirby KA 2012 The Journal of biological chemistry
Antiviral therapies: Focus on hepatitis B reverse transcriptase. Kirby KA 2012 The international journal of biochemistry & cell biology
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase. Kirby KA 2012 Antimicrobial agents and chemotherapy
Effect of translocation defective reverse transcriptase inhibitors on the activity of n348i, a connection subdomain drug resistant hiv-1 reverse transcriptase mutant. Kirby KA 2012 Cellular and molecular biology (Noisy-le-Grand, France)
Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase. Kirby KA 2011 Nucleic acids research
Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots. Kirby KA 2011 International journal of current chemistry
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. Kirby KA 2011 PloS one
The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase. Kirby KA 2011 Cellular and molecular biology (Noisy-le-Grand, France)
The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine. Kirby KA 2010 The Journal of biological chemistry
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