Welcome to the Polymerase Page

This page presents all the information in Polbase for TGO.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

TGO is a family B enzyme from Thermococcus gorgonarius.

Selected Properties for TGO:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (2) no data no data no data no data
Year Authors Title Results by property
2012 Christopher Cozens, Vitor B Pinheiro, Alexandra Vaisman, Roger Woodgate, Philipp Holliger Cozens C2012
2010 Tom Killelea, Samantak Ghosh, Samuel S Tan, Pauline Heslop, Susan J Firbank, Eric T Kool, Bernard A Connolly Killelea T2010
2009 Henry J Russell, Tomas T Richardson, Kieran Emptage, Bernard A Connolly Russell HJ2009 3-5' exo,5-3' exo,All properties
2008 Susan J Firbank, Josephine Wardle, Pauline Heslop, Richard J Lewis, Bernard A Connolly Firbank SJ2008
2004 Andrew F Gardner, Catherine M Joyce, William E Jack Gardner AF2004
1999 K P Hopfner, A Eichinger, R A Engh, F Laue, W Ankenbauer, R Huber, B Angerer Hopfner KP1999 Cloned or native,Full length or truncated,3-5' exo,Amino Acids Contacting NTP,Amino Acids Contacting Primer,All properties
Protein sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Tgo E664K
All Polymerases | 7 Results

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.