Welcome to the Polymerase Page

This page presents all the information in Polbase for TGO.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

TGO is a family B enzyme from Thermococcus gorgonarius.

Selected Properties for TGO:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (2) no data no data no data no data
Year Authors Title Results by property
2012 Christopher Cozens, Vitor B Pinheiro, Alexandra Vaisman, Roger Woodgate, Philipp Holliger Cozens C2012
2010 Tom Killelea, Samantak Ghosh, Samuel S Tan, Pauline Heslop, Susan J Firbank, Eric T Kool, Bernard A Connolly Killelea T2010
2009 Henry J Russell, Tomas T Richardson, Kieran Emptage, Bernard A Connolly Russell HJ2009 3-5' exo,5-3' exo,All properties
2008 Susan J Firbank, Josephine Wardle, Pauline Heslop, Richard J Lewis, Bernard A Connolly Firbank SJ2008
2004 Andrew F Gardner, Catherine M Joyce, William E Jack Gardner AF2004
1999 K P Hopfner, A Eichinger, R A Engh, F Laue, W Ankenbauer, R Huber, B Angerer Hopfner KP1999 Cloned or native,Full length or truncated,3-5' exo,Amino Acids Contacting NTP,Amino Acids Contacting Primer,All properties
Protein sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Tgo E664K
All Polymerases | 7 Results

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.