HIV RT M41L
From
HIV
Mutant of: HIV RT (M41L)
HIV RT M41L
is a family RT enzyme
from
HIV.
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:282|codon:ATG>TTG/CTG|drugs:AZT
From the Los Alamos National Labs HIV Mutant database (now offline):|id:985|codon:TAT>TTT|drugs:VRX-329747|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone
From the Los Alamos National Labs HIV Mutant database (now offline):|id:992|codon:TAT>TTT|drugs:VRX-413638|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone
Selected Properties for HIV RT M41L: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| no data | no data | no data | no data | no data |
- References (5)
- Structures (0)
- Sequences (0)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... |
Protein information: search for HIV RT M41L at UniProt
Sequence information: