HIV RT V75I

From HIV
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT V75I.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: HIV RT (V75I)

HIV RT V75I is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:358|codon:GTA>ATA|drugs:(-)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:1.6-fold after 12 passages From the Los Alamos National Labs HIV Mutant database (now offline):|id:359|codon:GTA>TTA|drugs:HBY 097|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Compensates for negative effect of G190E mutation on RT activity

Selected Properties for HIV RT V75I:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1999 N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Selection and characterization of HIV...
1996 Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess Selective pressure of a quinoxaline n...

Version:20241218

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.