HIV RT V75T

From HIV
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT V75T.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: HIV RT (V75T)

HIV RT V75T is a family RT enzyme from HIV. From the Los Alamos National Labs HIV Mutant database (now offline):|id:364|codon:GTA>ACA|drugs:d4C|class:Nucleoside RT Inhibitor (NRTI)|notes:d4T-selected "From the Los Alamos National Labs HIV Mutant database (now offline):|id:365|codon:GTA>ACA|drugs:d4T "From the Los Alamos National Labs HIV Mutant database (now offline):|id:366|codon:GTA>ACA|drugs:ddC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:367|codon:GTA>ACA|drugs:ddI "From the Los Alamos National Labs HIV Mutant database (now offline):|id:368|codon:GTA>ACA|drugs:(-)-FTC

Selected Properties for HIV RT V75T:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1999 P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno Stavudine resistance: an update on su...
1994 S F Lacey, Brendan A Larder Novel mutation (V75T) in human immuno...
1994 S F Lacey, Brendan A Larder Novel mutation (V75T) in human immuno...

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.