HIV RT K103T

From HIV
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT K103T.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: HIV RT (K103T)

HIV RT K103T is a family RT enzyme from HIV. From the Los Alamos National Labs HIV Mutant database (now offline):|id:415|codon:AAA>ACA|drugs:S-1153|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Low potency also against K103N/Y181C From the Los Alamos National Labs HIV Mutant database (now offline):|id:416|codon:AAA>ACA|drugs:UC-42|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:100-fold resistance

Selected Properties for HIV RT K103T:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1998 Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma Fujiwara T1998
1995 Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Balzarini J1995
All Polymerases | 0 Results

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.