HIV RT V118I

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Mutant of: HIV RT (V118I)

HIV RT V118I is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:440|codon:GTT>ATT|drugs:3TC From the Los Alamos National Labs HIV Mutant database (now offline):|id:988|codon:TAT>TTT|drugs:VRX-329747|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone From the Los Alamos National Labs HIV Mutant database (now offline):|id:995|codon:TAT>TTT|drugs:VRX-413638|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone

Selected Properties for HIV RT V118I:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2006 Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Novel nonnucleoside inhibitors that s...
2006 Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Novel nonnucleoside inhibitors that s...
2000 Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder A novel human immunodeficiency virus ...