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Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT T139I.


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Mutant of: HIV RT (T139I)

HIV RT T139I is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:457|codon:ACA>ATA|drugs:ADAMII|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:38-fold resistant against a virus isolate From the Los Alamos National Labs HIV Mutant database (now offline):|id:458|codon:ACA>ATA|drugs:Calanolide A|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:>70-fold resistance but not cross-resistant to other NNRTIs

Selected Properties for HIV RT T139I:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1998 Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit New alkenyldiarylmethanes with enhanc...
1995 Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader Resistance to 1-[(2-hydroxyethoxy)met...

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