HIV RT Y188L

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This page presents all the information in Polbase for HIV RT Y188L.

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Mutant of: HIV RT (Y188L)

HIV RT Y188L is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:541|codon:TAT>TTA|drugs:DMP-266 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:542|codon:TAT>?|drugs:DMP-266 From the Los Alamos National Labs HIV Mutant database (now offline):|id:543|codon:TAT>TTA|drugs:TIBO R82913|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:1000-fold increase in IC90

Selected Properties for HIV RT Y188L:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2000 L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski Human immunodeficiency virus type 1 m...
1995 S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll L-743, 726 (DMP-266): a novel, highly...
1994 A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne Characterization of HIV-1 strains iso...

Version:20241218

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