HIV RT G190E

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This page presents all the information in Polbase for HIV RT G190E.

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Mutant of: HIV RT (G190E)

HIV RT G190E is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:549|codon:GGA>GAA|drugs:AAP-BHAP "From the Los Alamos National Labs HIV Mutant database (now offline):|id:550|codon:GGA>GAA|drugs:DMP-266 From the Los Alamos National Labs HIV Mutant database (now offline):|id:551|codon:GGA>GAA|drugs:HBY 097|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Reduces enzymatic activity of RT and viral replication competency "From the Los Alamos National Labs HIV Mutant database (now offline):|id:552|codon:GGA>GAA|drugs:BI-RG-587 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:553|codon:GGA>GAA|drugs:S-2720 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:554|codon:GGA>GAA|drugs:UC-38

Selected Properties for HIV RT G190E:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2003 Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb Amino acid substitutions at position ...
2000 L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski Human immunodeficiency virus type 1 m...
1996 R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley (Alkylamino) piperidine bis(heteroary...
1995 Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis Preclinical evaluation of HBY 097, a ...
1995 Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Suppression of the breakthrough of hu...
1993 Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens Activity of a novel quinoxaline deriv...

Version:20241218

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