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Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT F227L.


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Mutant of: HIV RT (F227L)

HIV RT F227L is a family RT enzyme from HIV. From the Los Alamos National Labs HIV Mutant database (now offline):|id:584|codon:TTA>CTC|drugs:S-1153|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:V106A + F227L: 387-fold. This mutation confers hypersensitivity to delavirdine.

Selected Properties for HIV RT F227L:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1998 Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma S-1153 inhibits replication of known ...

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