HIV RT P236L

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Mutant of: HIV RT (P236L)

HIV RT P236L is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:587|codon:CCT>CTT|drugs:BHAP U-87201E "From the Los Alamos National Labs HIV Mutant database (now offline):|id:588|codon:CCT>CTT|drugs:BHAP U-90152 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:589|codon:CCT>CTT|drugs:HEPT|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Sensitizes RT ~10-fold to nevirapine

Selected Properties for HIV RT P236L:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1995 Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader Resistance to 1-[(2-hydroxyethoxy)met...
1993 T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley A mutation in reverse transcriptase o...
1993 T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley A mutation in reverse transcriptase o...