HIV RT P236L

From HIV
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT P236L.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: HIV RT (P236L)

HIV RT P236L is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:587|codon:CCT>CTT|drugs:BHAP U-87201E "From the Los Alamos National Labs HIV Mutant database (now offline):|id:588|codon:CCT>CTT|drugs:BHAP U-90152 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:589|codon:CCT>CTT|drugs:HEPT|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Sensitizes RT ~10-fold to nevirapine

Selected Properties for HIV RT P236L:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1995 Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader Buckheit RW1995
1993 T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley Dueweke TJ1993
1993 T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley Dueweke TJ1993
All Polymerases | 0 Results

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.