HIV RT M184I

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This page presents all the information in Polbase for HIV RT M184I.

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Mutant of: HIV RT (M184I)

HIV RT M184I is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:511|codon:ATG>ATA|drugs:3TC From the Los Alamos National Labs HIV Mutant database (now offline):|id:512|codon:ATG>ATA|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages From the Los Alamos National Labs HIV Mutant database (now offline):|id:513|codon:ATG>ATA|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages From the Los Alamos National Labs HIV Mutant database (now offline):|id:514|codon:ATG>ATA|drugs:(-)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages "From the Los Alamos National Labs HIV Mutant database (now offline):|id:515|codon:ATG>ATA|drugs:(-)-FTC From the Los Alamos National Labs HIV Mutant database (now offline):|id:516|codon:ATG>ATA|drugs:QYL-609|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:QYL-selected virus. From the Los Alamos National Labs HIV Mutant database (now offline):|id:517|codon:ATG>ATA|drugs:QYL-685|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:9-fold. Additional passage of virus did not select M184V "From the Los Alamos National Labs HIV Mutant database (now offline):|id:518|codon:ATG>ATG|drugs:QYL-685|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Additional passage of virus did not select M184V

Selected Properties for HIV RT M184I:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2013 Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg The Effect of Mutations at Position E...
2012 Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos Biochemical Mechanism of HIV-1 Resist...
2000 N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Selection and characterization of hum...
2000 D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando Drug resistance and drug combination ...
2000 N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Selection and characterization of hum...
1999 K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya In vitro induction of human immunodef...
1999 K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya In vitro induction of human immunodef...
1999 K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya In vitro induction of human immunodef...
1999 Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold Lamivudine (3TC) resistance in HIV-1 ...
1993 Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors Characterization of human immunodefic...
1993 M Tisdale, S D Kemp, N R Parry, Brendan A Larder Rapid in vitro selection of human imm...
1993 Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg The same mutation that encodes low-le...

Version:20241007

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