HIV RT M184I
From
HIV
Mutant of: HIV RT (M184I)
HIV RT M184I
is a family RT enzyme
from
HIV.
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:511|codon:ATG>ATA|drugs:3TC
From the Los Alamos National Labs HIV Mutant database (now offline):|id:512|codon:ATG>ATA|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages
From the Los Alamos National Labs HIV Mutant database (now offline):|id:513|codon:ATG>ATA|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages
From the Los Alamos National Labs HIV Mutant database (now offline):|id:514|codon:ATG>ATA|drugs:(-)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in <10 passages
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:515|codon:ATG>ATA|drugs:(-)-FTC
From the Los Alamos National Labs HIV Mutant database (now offline):|id:516|codon:ATG>ATA|drugs:QYL-609|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:QYL-selected virus.
From the Los Alamos National Labs HIV Mutant database (now offline):|id:517|codon:ATG>ATA|drugs:QYL-685|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:9-fold. Additional passage of virus did not select M184V
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:518|codon:ATG>ATG|drugs:QYL-685|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Additional passage of virus did not select M184V
Selected Properties for HIV RT M184I: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| no data | no data | no data | no data | no data |
- References (12)
- Structures (2)
- Sequences (0)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 1999 | K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1999 | K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1999 | K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... |
Protein information: search for HIV RT M184I at UniProt
Sequence information: