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Results for:
Polymerase: Pol eta Y52A
Polymerase | Reference | Property | Result | Context |
---|---|---|---|---|
Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Cloned or native | Cloned in yeast | |
Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Template lesions | Bypasses | Reaction: Nucleotide incorporation; Substrate: dNTPs; DNA lesion: TT Cyclobutane Pyrimidine Dimer |
Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | 3-5' Exonuclease (proofreading) | No | |
Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | 5-3' Exonuclease | No | |
Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Associated condition | UV sensitivity |
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