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Reference: Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta., Polymerase: Pol eta Y52A
| Polymerase | Reference | Property | Result | Context |
|---|---|---|---|---|
| Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | 3-5' Exonuclease (proofreading) | No | |
| Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Template lesions | Bypasses | Reaction: Nucleotide incorporation; Substrate: dNTPs; DNA lesion: TT Cyclobutane Pyrimidine Dimer |
| Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Associated condition | UV sensitivity | |
| Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | 5-3' Exonuclease | No | |
| Pol eta Y52A | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. | Cloned or native | Cloned in yeast |
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