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Steitz TA

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Publications:

Title Authors Year Journal
Insights into Base Selectivity from the 1.8 A Resolution Structure of an RB69 DNA Polymerase Ternary Complex. Steitz TA 2011 Biochemistry
Insights into the replisome from the structure of a ternary complex of the DNA polymerase III alpha-subunit. Steitz TA 2008 Journal of molecular biology
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases. Steitz TA 2007 The EMBO journal
The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition. Steitz TA 2006 The EMBO journal
Visualizing polynucleotide polymerase machines at work. Steitz TA 2006 The EMBO journal
The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Steitz TA 2006 Cell
Correction of X-ray intensities from single crystals containing lattice-translocation defects. Steitz TA 2005 Acta Crystallogr D Biol Crystallogr
A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Steitz TA 2005 Proceedings of the National Academy of Sciences of the United States of America
Accuracy, lesion bypass, strand displacement and translocation by DNA polymerases. Steitz TA 2004 Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29. Steitz TA 2004 Molecular cell
Assembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex. Steitz TA 2002 Nucleic acids research
Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Steitz TA 2002 Cell
Structure of the replicating complex of a pol alpha family DNA polymerase. Steitz TA 2001 Cell
Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain. Steitz TA 2001 Molecular cell
Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Steitz TA 1999 Cell
DNA polymerases: structural diversity and common mechanisms. Steitz TA 1999 The Journal of biological chemistry
Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment. Steitz TA 1999 Chemistry & biology
Structural basis for initiation of transcription from an RNA polymerase-promoter complex. Steitz TA 1999 Nature
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. Steitz TA 1999 Biochemistry
A mechanism for all polymerases. Steitz TA 1998 Nature
Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. Steitz TA 1998 Journal of molecular biology
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. Steitz TA 1998 The EMBO journal
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes. Steitz TA 1998 Current opinion in structural biology
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Steitz TA 1997 Cell
Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions. Steitz TA 1996 Biochemistry
Structure of Taq polymerase with DNA at the polymerase active site. Steitz TA 1996 Nature
Crystallization and preliminary X-ray crystallographic analysis of DNA polymerase from Thermus aquaticus. Steitz TA 1995 Acta crystallographica. Section D, Biological crystallography
Polymerase structures and function: variations on a theme? Steitz TA 1995 J Bacteriol
Crystal structure of Thermus aquaticus DNA polymerase. Steitz TA 1995 Nature
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA. Steitz TA 1995 Nature
Function and structure relationships in DNA polymerases. Steitz TA 1994 Annu Rev Biochem
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Steitz TA 1994 Proceedings of the National Academy of Sciences of the United States of America
Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion. Steitz TA 1994 Structure (London, England : 1993)
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. Steitz TA 1994 Proceedings of the National Academy of Sciences of the United States of America
Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Steitz TA 1993 Cold Spring Harbor symposia on quantitative biology
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Steitz TA 1993 Biochemistry
A general two-metal-ion mechanism for catalytic RNA. Steitz TA 1993 Proceedings of the National Academy of Sciences of the United States of America
Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Steitz TA 1993 Science
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Steitz TA 1992 Science
Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. Steitz TA 1992 Proceedings of the National Academy of Sciences of the United States of America
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. Steitz TA 1991 The EMBO journal
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. Steitz TA 1990 The Journal of biological chemistry
Cocrystal structure of an editing complex of Klenow fragment with DNA. Steitz TA 1988 Proceedings of the National Academy of Sciences of the United States of America
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. Steitz TA 1988 Science
Structural studies of Klenow fragment: an enzyme with two active sites. Steitz TA 1987 Cold Spring Harbor symposia on quantitative biology
Functional implications of the Klenow fragment structure. Steitz TA 1986 Biochem Soc Trans
A domain of the Klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity. Steitz TA 1986 Proteins
Electrostatic field of the large fragment of Escherichia coli DNA polymerase I. Steitz TA 1985 Journal of molecular biology
Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase. Steitz TA 1985 Nature
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. Steitz TA 1985 Nature
Crystallographic studies of protein-nucleic acid interaction: catabolite gene activator protein and the large fragment of DNA polymerase I. Steitz TA 1983 Journal of biomolecular structure & dynamics
Crystallization and 7 A resolution electron density map of the large fragment of Escherichia coli DNA polymerase I. Steitz TA 1983 Journal of molecular biology

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