show help

Schlick T

Author page

This page provides a summary of the entries in Polbase associated with this author.

The publication history graph presents the number of publications in Polbase by this author over time.

The polymerase chart indicates which polymerases this author has published on.

Polbase automatically discovers many polymerase papers as they are published. Some relevant papers are not included because the algorithm is designed to reduce background. Please contribute to polbase by adding your missing DNA polymerase papers.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Missing references?


Title Authors Year Journal
Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms. Schlick T 2012 Theoretical chemistry accounts
Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway. Schlick T 2012 Journal of the American Chemical Society
Modeling DNA polymerase μ motions: subtle transitions before chemistry. Schlick T 2010 Biophysical journal
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Schlick T 2008 EMBO Rep
Quantum mechanics/molecular mechanics investigation of the chemical reaction in Dpo4 reveals water-dependent pathways and requirements for active site reorganization. Schlick T 2008 Journal of the American Chemical Society
A quantum mechanical investigation of possible mechanisms for the nucleotidyl transfer reaction catalyzed by DNA polymerase beta. Schlick T 2007 J Phys Chem B
DNA polymerase beta catalysis: are different mechanisms possible? Schlick T 2007 Journal of the American Chemical Society
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. Schlick T 2007 Biophys J
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides. Schlick T 2007 BMC Struct Biol
Sequential side-chain residue motions transform the binary into the ternary state of DNA polymerase lambda. Schlick T 2006 Biophys J
Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass. Schlick T 2006 Protein science : a publication of the Protein Society
In silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanism. Schlick T 2006 Biophys J
Correct and incorrect nucleotide incorporation pathways in DNA polymerase beta. Schlick T 2006 Biochem Biophys Res Commun
Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Schlick T 2006 Biochemistry
Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity. Schlick T 2005 Biochemistry
Fidelity discrimination in DNA polymerase beta: differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair. Schlick T 2005 Journal of the American Chemical Society
Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing. Schlick T 2004 Proceedings of the National Academy of Sciences of the United States of America
In silico evidence for DNA polymerase-beta's substrate-induced conformational change. Schlick T 2004 Biophys J
Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses. Schlick T 2004 Biophys J
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly. Schlick T 2004 Journal of the American Chemical Society
Polymerase beta simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se. Schlick T 2002 Journal of molecular biology
Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus. Schlick T 2002 Journal of molecular biology
All Authors

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.