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Beese LS

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Publications:

Title Authors Year Journal
The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. Beese LS 2010 Structure (London, England : 1993)
Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Beese LS 2009 Biochemistry
Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Beese LS 2007 Nucleic acids research
The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. Beese LS 2006 Proceedings of the National Academy of Sciences of the United States of America
Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. Beese LS 2005 The Journal of biological chemistry
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Beese LS 2004 Nature
Structures of mismatch replication errors observed in a DNA polymerase. Beese LS 2004 Cell
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. Beese LS 2004 The Journal of biological chemistry
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Beese LS 2003 Proceedings of the National Academy of Sciences of the United States of America
Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. Beese LS 2000 Journal of molecular biology
Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. Beese LS 1998 Acta Crystallogr D Biol Crystallogr
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Beese LS 1998 Nature
Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution. Beese LS 1997 Structure (London, England : 1993)
Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Beese LS 1993 Cold Spring Harbor symposia on quantitative biology
Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Beese LS 1993 Science
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Beese LS 1993 Biochemistry
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. Beese LS 1991 The EMBO journal
Cocrystal structure of an editing complex of Klenow fragment with DNA. Beese LS 1988 Proceedings of the National Academy of Sciences of the United States of America
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