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Preston BD

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Publications:

Title Authors Year Journal
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Preston BD 2009 Proceedings of the National Academy of Sciences of the United States of America
Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Preston BD 2007 Molecular and cellular biology
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions. Preston BD 2007 Nucleic acids research
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta. Preston BD 2006 The Journal of biological chemistry
Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. Preston BD 2006 The Journal of biological chemistry
Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors. Preston BD 2002 Molecular pharmacology
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Preston BD 2002 Proceedings of the National Academy of Sciences of the United States of America
Mutational analysis of HIV-1 long terminal repeats to explore the relative contribution of reverse transcriptase and RNA polymerase II to viral mutagenesis. Preston BD 2002 The Journal of biological chemistry
Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice. Preston BD 2001 Nat Med
A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine. Preston BD 1999 Antimicrobial agents and chemotherapy
A genetic system to identify DNA polymerase beta mutator mutants. Preston BD 1997 Proceedings of the National Academy of Sciences of the United States of America
Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA. Preston BD 1997 The Journal of biological chemistry
Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site. Preston BD 1996 Journal of virology
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. Preston BD 1991 Proceedings of the National Academy of Sciences of the United States of America
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. Preston BD 1989 Proceedings of the National Academy of Sciences of the United States of America
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Preston BD 1989 Molecular and cellular biology
Fidelity of HIV-1 reverse transcriptase. Preston BD 1988 Science
O-Alkyl deoxythymidines are recognized by DNA polymerase I as deoxythymidine or deoxycytidine. Preston BD 1987 IARC Sci Publ
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. Preston BD 1986 Proceedings of the National Academy of Sciences of the United States of America

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