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Romano LJ

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Publications:

Title Authors Year Journal
Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment. Romano LJ 2014 Nucleic acids research
Carcinogenic adducts induce distinct DNA polymerase binding orientations. Romano LJ 2013 Nucleic acids research
Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. Romano LJ 2012 Nucleic acids research
Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Romano LJ 2009 Proceedings of the National Academy of Sciences of the United States of America
Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Romano LJ 2009 Biochemistry
The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Romano LJ 2007 Biochemistry
Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment). Romano LJ 2005 Biochemistry
Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Romano LJ 2004 Proceedings of the National Academy of Sciences of the United States of America
Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment). Romano LJ 2002 Biochemistry
Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation. Romano LJ 2001 Biochemistry
In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass. Romano LJ 2000 Biochemistry
A conformational change in E. coli DNA polymerase I (Klenow fragment) is induced in the presence of a dNTP complementary to the template base in the active site. Romano LJ 2000 Biochemistry
Differential effects of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts on the conformational change in the structure of DNA polymerase I (Klenow fragment). Romano LJ 2000 Biochemistry
Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site. Romano LJ 1999 The Journal of biological chemistry
Differences in the mechanism of stimulation of T7 DNA polymerase by two binding modes of Escherichia coli single-stranded DNA-binding protein. Romano LJ 1995 The Journal of biological chemistry
Accurate in vitro translesion synthesis by Escherichia coli DNA polymerase I (large fragment) on a site-specific, aminofluorene-modified oligonucleotide. Romano LJ 1991 Carcinogenesis
Mechanism of stimulation of T7 DNA polymerase by Escherichia coli single-stranded DNA binding protein (SSB). Romano LJ 1988 The Journal of biological chemistry
Contrasting effects of Escherichia coli single-stranded DNA binding protein on synthesis by T7 DNA polymerase and Escherichia coli DNA polymerase I (large fragment). Evidence that binding protein inhibits trans-lesion synthesis by polymerase I. Romano LJ 1986 The Journal of biological chemistry
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase. Romano LJ 1981 Proceedings of the National Academy of Sciences of the United States of America
Requirements for synthesis of ribonucleic acid primers during lagging strand synthesis by the DNA polymerase and gene 4 protein of bacteriophage T7. Romano LJ 1979 The Journal of biological chemistry
Characterization of the ribonucleic acid primers and the deoxyribonucleic acid product synthesized by the DNA polymerase and gene 4 protein of bacteriophage T7. Romano LJ 1979 The Journal of biological chemistry
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