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Aggarwal AK

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Publications:

Title Authors Year Journal
The Architecture of Yeast DNA Polymerase ζ Aggarwal AK 2013 Cell reports
An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε Aggarwal AK 2013 Journal of molecular biology
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Aggarwal AK 2012 Nature structural & molecular biology
Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis. Aggarwal AK 2011 Journal of molecular biology
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. Aggarwal AK 2011 Journal of molecular biology
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. Aggarwal AK 2011 Journal of molecular biology
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Aggarwal AK 2010 Structure (London, England : 1993)
Structural basis for the suppression of skin cancers by DNA polymerase eta. Aggarwal AK 2010 Nature
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. Aggarwal AK 2009 Journal of molecular biology
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Aggarwal AK 2009 Nature structural & molecular biology
DNA synthesis across an abasic lesion by human DNA polymerase iota. Aggarwal AK 2009 Structure (London, England : 1993)
Replication across template T/U by human DNA polymerase-iota. Aggarwal AK 2009 Structure (London, England : 1993)
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Aggarwal AK 2009 PloS one
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Aggarwal AK 2008 Structure (London, England : 1993)
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Aggarwal AK 2007 Molecular cell
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Aggarwal AK 2006 Nature structural & molecular biology
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Aggarwal AK 2006 Structure (London, England : 1993)
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Aggarwal AK 2005 Structure (London, England : 1993)
Rev1 employs a novel mechanism of DNA synthesis using a protein template. Aggarwal AK 2005 Science (New York, N.Y.)
Dpo4 is hindered in extending a G.T mismatch by a reverse wobble. Aggarwal AK 2004 Nature structural & molecular biology
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Aggarwal AK 2004 Nature
Crystal structure of the catalytic core of human DNA polymerase kappa. Aggarwal AK 2004 Structure (London, England : 1993)
Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases. Aggarwal AK 2003 Molecular and cellular biology
Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis. Aggarwal AK 2001 Molecular cell
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