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Seki M

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Publications:

Title Authors Year Journal
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Seki M 2011 Journal of molecular biology
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Seki M 2010 Proceedings of the National Academy of Sciences of the United States of America
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Seki M 2010 Nucleic acids research
Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Seki M 2009 Radiat Res
Low-fidelity DNA synthesis by human DNA polymerase theta. Seki M 2008 Nucleic acids research
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. Seki M 2008 DNA repair
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. Seki M 2007 The Journal of biological chemistry
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Seki M 2006 Molecular cell
High-efficiency bypass of DNA damage by human DNA polymerase Q. Seki M 2004 The EMBO journal
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Seki M 2003 Nucleic acids research
The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta. Seki M 2002 Mol Genet Genomics
Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli. Seki M 1999 The Journal of biological chemistry
Stimulation of DNA synthesis by mouse DNA helicase B in a DNA replication system containing eukaryotic replication origins. Seki M 1995 Biochemistry
Detection and characterization of a novel factor that stimulates DNA polymerase alpha. Seki M 1986 Biochemistry
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