Low-fidelity DNA synthesis by human DNA polymerase theta.
Nucleic acids research (2008), Volume 36, Page 3847
Abstract:
Polymerases:
Topics:
Historical Protein Properties (MW, pI, ...), Fidelity, Exonuclease Activity, Source / Purification
Status:
new | topics/pols set | partial results | complete | validated |
Results:
Polymerase | Reference | Property | Result | Context |
---|---|---|---|---|
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | Molecular Weight | 290kD | |
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | 3-5' Exonuclease (proofreading) | No | |
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | Overall Error Rate | 0.0014 errors/bp | Technique: M13mp2 forward mutation assay (Single base deletions) |
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | Overall Error Rate | 0.0033 errors/bp | Technique: M13mp2 forward mutation assay (Single base additions) |
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | Nucleotide Substitution Rate | 0.0024 errors/bp | Technique: M13mp2 forward mutation assay |
Human Pol theta | Low-fidelity DNA synthesis by human DNA polymerase theta. | Full length or truncated | Full length |