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Prasad VR

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Publications:

Title Authors Year Journal
Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. Prasad VR 2008 PloS one
Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. Prasad VR 2007 Journal of molecular biology
The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity. Prasad VR 2007 Nucleic acids research
Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. Prasad VR 2006 The Journal of biological chemistry
Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates. Prasad VR 2004 Int J Biochem Cell Biol
Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase. Prasad VR 2002 The Journal of biological chemistry
Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase. Prasad VR 2000 The Journal of biological chemistry
The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency. Prasad VR 1998 Nucleic acids research
Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus? Prasad VR 1998 Journal of molecular medicine (Berlin, Germany)
Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. Prasad VR 1997 Journal of molecular biology
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Prasad VR 1997 Nucleic acids research
The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors. Prasad VR 1996 Antimicrobial agents and chemotherapy
Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase. Prasad VR 1996 J Virol
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Prasad VR 1996 Science (New York, N.Y.)
Use of chimeric human immunodeficiency virus types 1 and 2 reverse transcriptases for structure-function analysis and for mapping susceptibility to nonnucleoside inhibitors. Prasad VR 1996 Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. Prasad VR 1991 Proceedings of the National Academy of Sciences of the United States of America

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