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Marchand B

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Publications:

Title Authors Year Journal
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA. Marchand B 2013 Retrovirology
Effects of 4' - and 2-Substitutions on the Bioactivity of 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine. Marchand B 2013 Antimicrobial agents and chemotherapy
Effect of translocation defective reverse transcriptase inhibitors on the activity of n348i, a connection subdomain drug resistant hiv-1 reverse transcriptase mutant. Marchand B 2012 Cellular and molecular biology (Noisy-le-Grand, France)
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine. Marchand B 2012 The Journal of biological chemistry
HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors. Marchand B 2012 The Journal of biological chemistry
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase. Marchand B 2012 Antimicrobial agents and chemotherapy
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates. Marchand B 2011 Nucleic acids research
The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase. Marchand B 2011 Cellular and molecular biology (Noisy-le-Grand, France)
Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase. Marchand B 2011 Nucleic acids research
The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine. Marchand B 2010 The Journal of biological chemistry
Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions. Marchand B 2010 Biochimica et biophysica acta
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. Marchand B 2009 Journal of molecular biology
Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Marchand B 2007 Antimicrob Agents Chemother
The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. Marchand B 2007 The Journal of biological chemistry
Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase. Marchand B 2005 Antimicrob Agents Chemother
Impact of the translocational equilibrium of HIV-1 reverse transcriptase on the efficiency of mismatch extensions and the excision of mispaired nucleotides. Marchand B 2004 Int J Biochem Cell Biol
Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC. Marchand B 2003 The Journal of biological chemistry
Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance. Marchand B 2003 The Journal of biological chemistry
Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity. Marchand B 2003 Journal of virology
Nonradioactive detection of retroviral-associated RNase H activity in a microplate-based, high-throughput format. Marchand B 2002 BioTechniques

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