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Fowler JD

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Publications:

Title Authors Year Journal
Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase. Fowler JD 2012 Chemical research in toxicology
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases. Fowler JD 2011 Antimicrobial agents and chemotherapy
Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Fowler JD 2011 Nucleic acids research
Backbone assignment of the little finger domain of a Y-family DNA polymerase. Fowler JD 2011 Biomolecular NMR assignments
Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase lambda. Fowler JD 2010 Journal of molecular biology
Backbone assignment of the catalytic core of a Y-family DNA polymerase. Fowler JD 2010 Biomol NMR Assign
Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. Fowler JD 2010 Biochemistry
A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. Fowler JD 2010 Journal of molecular biology
Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2. Fowler JD 2010 Biochemistry
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. Fowler JD 2009 The Journal of biological chemistry
Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting. Fowler JD 2009 Journal of molecular biology
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. Fowler JD 2008 The Journal of biological chemistry
Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Fowler JD 2007 Journal of molecular biology
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