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Yadav PN

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Publications:

Title Authors Year Journal
Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis. Yadav PN 2000 Biochemistry
Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase. Yadav PN 1998 The Journal of biological chemistry
Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif. Yadav PN 1998 Biochemistry
Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis. Yadav PN 1997 Biochemistry
Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase. Yadav PN 1996 Biochemistry
Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. Yadav PN 1996 Biochemistry
Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies. Yadav PN 1996 Drug design and discovery
Nucleoside drug resistance in HIV-1 reverse transcriptase. Yadav PN 1995 Nature structural biology
A computer-assisted analysis of conserved residues in the three-dimensional structures of the polymerase domains of Escherichia coli DNA polymerase I and HIV-1 reverse transcriptase. Yadav PN 1994 The Journal of biological chemistry
Identification and analysis of a template-primer (ds-DNA) binding cleft in E. coli DNA polymerase I: an electrostatic potential contour pattern of the modeled structure. Yadav PN 1994 J Mol Recognit
Identification of a pharmacophore for nucleoside analog inhibitors directed at HIV-1 reverse transcriptase. Yadav PN 1994 Journal of molecular recognition : JMR
A molecular model of the complete three-dimensional structure of the Klenow fragment of Escherichia coli DNA polymerase I: binding of the dNTP substrate and template-primer. Yadav PN 1992 Biochemistry
Binding of DNA to large fragment of DNA polymerase I: identification of strong and weak electrostatic forces and their biological implications. Yadav PN 1992 J Biomol Struct Dyn
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