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Frenkel YV

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Publications:

Title Authors Year Journal
Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening. Frenkel YV 2013 Journal of medicinal chemistry
Structural basis of HIV-1 resistance to AZT by excision. Frenkel YV 2010 Nature structural & molecular biology
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations. Frenkel YV 2008 Proceedings of the National Academy of Sciences of the United States of America
Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability. Frenkel YV 2005 J Med Chem
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine). Frenkel YV 2005 J Med Chem

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