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Farr CL

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Publications:

Title Authors Year Journal
Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster. Farr CL 2013 Archives of insect biochemistry and physiology
Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G. Farr CL 2010 Biochimica et biophysica acta
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion. Farr CL 2008 Journal of neurochemistry
A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Farr CL 2006 Journal of molecular biology
Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome. Farr CL 2005 Human molecular genetics
Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein. Farr CL 2004 The Journal of biological chemistry
The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster. Farr CL 2002 Proceedings of the National Academy of Sciences of the United States of America
Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. DNA polymerase gamma. Farr CL 2002 Methods in molecular biology (Clifton, N.J.)
Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis. Farr CL 1999 The Journal of biological chemistry
Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme. Farr CL 1997 The Journal of biological chemistry
Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization. Farr CL 1996 The Journal of biological chemistry
Mitochondrial single-stranded DNA-binding protein from Drosophila embryos. Physical and biochemical characterization. Farr CL 1995 The Journal of biological chemistry
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