A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase.
Journal of molecular biology (2006), Volume 358, Page 1229
Abstract:
Polymerases:
Topics:
Kinetic Parameters, Structure and Structure/Function, Nucleotide Incorporation, Exonuclease Activity
Status:
new | topics/pols set | partial results | complete | validated |
Results:
Polymerase | Reference | Property | Result | Context |
---|---|---|---|---|
Human Pol gamma | A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. | 3-5' Exonuclease (proofreading) | Yes | |
Human Pol gamma | A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. | Processivity | 586bp | |
Human Pol gamma | A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. | Kd | 10.2nM | Reaction: Polymerase-DNA interaction; Substrate: DNA template |