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Marquez VE

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Publications:

Title Authors Year Journal
Effects of 4' - and 2-Substitutions on the Bioactivity of 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine. Marquez VE 2013 Antimicrobial agents and chemotherapy
A nucleotide analogue induced gain of function corrects the error-prone nature of human DNA polymerase iota. Marquez VE 2012 Journal of the American Chemical Society
Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues. Marquez VE 2012 Biochemistry
Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Marquez VE 2010 Angewandte Chemie (International ed. in English)
The nucleoside analogue D-carba T blocks HIV-1 reverse transcription. Marquez VE 2009 Journal of medicinal chemistry
The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants. Marquez VE 2007 Journal of molecular biology
Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker. Marquez VE 2004 Journal of the American Chemical Society
A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides. Marquez VE 2004 J Med Chem
A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Marquez VE 2003 Journal of medicinal chemistry
Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase. Marquez VE 2000 Biochemistry

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