| Interaction of cis-diamminedichloroplatinum (II) with single-stranded DNA in the presence or absence of Escherichia coli single-stranded binding protein. |
Hoffmann JS, Hübscher U, Michot B, Villani G |
1991 |
| Anti-human immunodeficiency virus effects of cationic metalloporphyrin-ellipticine complexes. |
Ding L, Balzarini J, Schols D, Meunier B, De Clercq E |
1992 |
| 4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. |
Togashi H, Mizushina Y, Takemura M, Sugawara F, Koshino H, Esumi Y, Uzawa J, Kumagai H, Matsukage A, Yoshida S, Sakaguchi K |
1998 |
| Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum. |
Mizushina Y, Watanabe I, Ohta K, Takemura M, Sahara H, Takahashi N, Gasa S, Sugawara F, Matsukage A, Yoshida S, Sakaguchi K |
1998 |
| Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid. |
Mizushina Y, Murakami C, Ohta K, Takikawa H, Mori K, Yoshida H, Sugawara F, Sakaguchi K |
2002 |
| Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo. |
Liu X, Huang H, Wang J, Wang C, Wang M, Zhang B, Pan C |
2011 |
| Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG). |
Murakami C, Miuzno T, Hanaoka F, Yoshida H, Sakaguchi K, Mizushina Y |
2004 |
| Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases. |
Murakami C, Takemura M, Yoshida H, Sugawara F, Sakaguchi K, Mizushina Y |
2003 |
| Effects of glycolipids from spinach on mammalian DNA polymerases. |
Murakami C, Kumagai T, Hada T, Kanekazu U, Nakazawa S, Kamisuki S, Maeda N, Xu X, Yoshida H, Sugawara F, Sakaguchi K, Mizushina Y |
2003 |
| Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. |
Zanoli S, Gemma S, Butini S, Brindisi M, Joshi BP, Campiani G, Fattorusso C, Persico M, Crespan E, Cancio R, Spadari S, Hübscher U, Maga G |
2008 |
| Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. |
Hatse S, De Clercq E, Balzarini J |
1999 |
| Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. |
De Clercq E |
2004 |
| Suppression of resistance to drugs targeted to human immunodeficiency virus reverse transcriptase by combination therapy. |
Balzarini J |
1999 |
| Alpha, beta- and beta, gamma-methylene 5'-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine-5'-triphosphate. Correlation between affinity for reverse transcriptase, susceptibility to hydrolysis by phosphodiesterases and anti-retrovirus activity. |
Balzarini J, Herdewijn P, Pauwels R, Broder S, De Clercq E |
1988 |
| HIV resistance to reverse transcriptase inhibitors. |
De Clercq E |
1994 |
| Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication. |
Neyts J, De Clercq E |
1994 |
| Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells. |
Törnevik Y, Ullman B, Balzarini J, Wahren B, Eriksson S |
1995 |
| Dancing with chemical formulae of antivirals: a personal account. |
De Clercq E |
2013 |